Learn genetic tests and gene mutations

Nowadays, genetic testing is increasingly popular. The reason is that not only helps to detect hidden cancer factors through genetic mutations, this test also helps you better understand yourself such as personality, weight, height. Understand the need for testing. Genetics of many customers, CarePlus is now offering a wide variety of genetic testing packages at an attractive cost.

Genetic testing has many incredible benefits for your health

1. List of genetic test packages at CarePlus and their advantages

CarePlus is an international clinic system operated by CityClinic Vietnam Company Limited with 100% foreign capital. In addition to examination packages such as adult general health check-up, comprehensive gynecological examination, early puberty checkup in children. Currently CarePlus also provides genetic testing packages with outstanding advantages:

1.1. GenePlus Fitness and Lifestyle Test

Many misconceptions are that genes only regulate the appearance of a person such as an eye color, hair color, facial features (eg, small eyes, high nose, small mouth) But in fact, genes affect more than that, including personality, weight, height, absorption or drug resistance So, some genetic tests will help you better understand yourself. From there, there is a more suitable self-care.

CarePlus Health and Lifestyle GenePlus Test Package provide you with a complete and easy-to-understand profile of more than 75 types of genetic tests related to your body condition. Specifically:

• Ancestors (3 categories): Ancestor groups, Ancient Ancestors, Matriarchal haploid groups

• Physical and athletic ability (17 categories): Endurance, strength, the effects of exercise, and diet on weight, ability to improve heart rate, VO2max, disc health. 

• Nutrition and metabolism (9 categories): caffeine, alcohol, calcium, Vitamin A metabolism

• Drug response (6 categories): Statins, Losartan, Nitroglycerin, Warfarin

• Potential pathogenic genes (6 categories): Mediterranean fever with family type B, cystic fibrosis, color blindness, Fructose tolerance disorder

• Physical characteristics (13 categories): Reaction to alcohol, tobacco addiction, menopause, eating habits, fasting blood sugar

• Health risks such as diabetes, cancer, heart disease, obesity (21 categories): Atrial fibrillation, Stomach cancer, Hypertension, Kidney cancer, Lung cancer, Obesity, Diabetes Type 1 and Type 2 sugars, Non-alcoholic fatty liver disease 

This test helps you understand the body to have the right eating, exercise, lifestyle adjustment

1.2. Genetic cancer testing through genetic mutations

Each individual gene in DNA is responsible for establishing a cell's structure, function, and capacity. Any structural defect can lead to cell dysfunction. At this point, the mutant gene would prompt a normal cell to grow and divide rapidly uncontrollably to create many new cells with the same mutation.

Mutations in the inhibitory gene allow cancer cells to grow and divide continuously. More seriously, gene-corrected DNA mutations mean that faulty genes are not corrected like in a normal cell DNA, making the cell more prone to cancer.

In addition to factors: smoking, radioactivity, viruses, cancer-causing chemicals, obesity, hormones, chronic inflammation ... genetic mutations due to congenital (inherited mutant genome from parents, ancestors) 10% causes some types of cancer.

Genetic testing can also detect potential cancer risk 

GenePlus test for breast and ovarian cancer (2 genes)

Breast and ovarian cancers are extremely common cancers. Studies show that mutations of the BRCA1 and BRCA2 genes in stem cells are a factor that increases the risk of these two types of cancer. Not stopping there, mutations BRCA1 and BRCA2 are also the cause of 15% of all ovarian cancer cases.

CarePlus's GenePlus screening for breast and ovarian cancer (2 genes) will focus on mutations of the BRCA1 and BRCA2 genes. So you can rest assured that any dangerous mutation in even the smallest of two genes is not ignored.

GenePlus test for breast and ovarian cancer (26 genes)

Not only BRCA1 and BRCA2, but breast and ovarian cancers can also be caused by other genetic mutations. The GenePlus test package for breast and ovarian cancer (26 genes) will help you check for these genes, specifically:

• BRCA1

• BRCA2

• CHEK2

• PALB2

• BRIP1

• TP53

• PTEN

• STK11

• CDH1

• ATM

• BARD1

• MLH1

• MRE11A

• MSH2

• MSH6

• MUTYH

• NBN

• PMS1

• PMS2

• RAD50

• RAD51C

• RAD51D

• NF1

• EPCAM

• SMARCA4

• HOXB13

The GenePlus test checks for genetic cancer 79 genes for men and women

Cancer can be well prevented and controlled if detected early. The 79-gene GenePlus test analyzes markers for mutations in 79 genes that screen for the risk of up to 19 inherited cancers. The list of cancers that can be detected through the CarePlus genetic testing package:

Hereditary risk of cancer in men

• Breast.

• Stomach.

• Kidney.

• Prostate.

• Endocrine glandular polyps.

• Thyroid.

• Parathyroid glands.

• Nervous fibroids.

• Adrenal medullary tumors.

• Nerve parathyroid cells.

• Retinoblastoma.

• Melanoma.

• Cartilage.

• Colorectal.

• Pancreas.

• Gastrointestinal stromal tumors.

Hereditary risk of cancer in women

• Breast.

• Ovary.

• Stomach.

• Kidney.

• Endocrine glandular polyps.

• Thyroid.

• Parathyroid glands.

• Nervous fibroids.

• Adrenal medullary tumors.

• Nerve parathyroid cells.

• Retinoblastoma.

• Melanoma.

• Cartilage.

• Colorectal.

• Pancreas.

• Endometrium.

• Gastrointestinal stromal tumors.

2. What are the steps to test at CarePlus?

The test process at CarePlus includes 6 steps as follows:

3. Why is the genetic test at CarePlus chosen by many customers?

High reliability

All tests and analyzes are submitted and performed at the CAP standard laboratory in Hong Kong. At the same time, applying new generation gene sequencing technology NGS, meeting standards of the College of American Pathologists, and ISO certification of information security and management systems.

Specialized for Asians

In addition to the global genetic data, CarePlus also cooperates with BGI - GenBank specialized for Asians - so it is possible to access the most comprehensive and appropriate Asian genetic data. Therefore, customers can be completely assured of the results of the examination package.

An international team of experts

Genetic test results have all been analyzed by international experts from Hong Kong and Singapore. At the same time, the CarePlus genetic counselor will guide in detail the test procedure as well as explain the results, along with giving advice on the right healthcare method for you.

4. What should I do when I know I have a cancer gene?

If a person is diagnosed with cancer risk, the doctor will do tests on a sample of cancer cells to look for certain genetic changes. These tests can sometimes provide information about incidence and help a doctor know what type of treatment is right for them.

The doctor or advise you the right solutions when detecting cancer genes

At CarePlus, doctors will provide detailed counseling and control to minimize the risk of genetic cancer based on test results, family history and many other factors. Not only that, CarePlus doctors also advise on preventive methods that can include: medical intervention, drug use, regular screening and lifestyle changes.

The following are the cancer screening packages at CarePlus:

• Screening for cervical cancer.

• Screening for lung cancer.

• Screening for stomach cancer.

• Screening for cancer is common in women (breast, uterus, ovaries).

• Screening for nasopharyngeal cancer.

• Comprehensive cancer screening for women.

• Comprehensive cancer screening for men.

5. Who should get genetic testing?

Genetic testing is essential, especially for the following subjects:

- Have a family history of cancer.

- Want to know if you have inherited a bad gene that increases your risk of cancer or not?

- Want to know if I pass on bad genes to my children or not?

- Want to maintain a healthy lifestyle through proactive prevention.

Genetic testing has many benefits for people doing it. Among the highlights is to help testers better understand themselves and detect genetic mutations early (if any). Today, contact CarePlus to get more details about the packages as well as make an appointment with your doctor:

• Hotline: 1800 6116

• Email: info@careplusvn.com

• Fanpage: CarePlus Clinic Vietnam